Osteoclasts: New Insights

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New Insights on Genetic Features of Neu-Laxova Syndrome

ABSTRACTBackground: This study aimed to present a rare case of Neu-Laxova syndrome (NLS) and review the newly revealed genetic features of the disease in hopes to find a way for early interventions.Case report: Female newborn with NLS was born at 30 weeks of gestation to consanguineous parents. The last prenatal ultrasound imaging revealed severe intrauterine growth restriction and microcephaly...

متن کامل

New insights

Heart rate turbulence (HRT) is a measure of the autonomic response to perturbations of arterial blood pressure after single ventricular premature complex (VPC). This response consists of a short initial acceleration followed by a gradual deceleration of the heart rate1. One of the mechanisms proposed for the genesis of HRT is the alteration in the baroreceptor reflex elicited by the small drop ...

متن کامل

Osteoclasts, mononuclear phagocytes, and c-Fos: new insight into osteoimmunology.

Osteoimmunology is the emerging concept that certain molecules link the skeletal and immune systems. The transcription factor c-Fos, a component of activator protein-1 (AP-1), is essential for osteoclast differentiation. Mice lacking c-Fos are osteopetrotic owing to impaired osteoclast development. Recent studies suggest that in contrast to this positive role in osteoclastogenesis, c-Fos expres...

متن کامل

New Insights

Throughout history, alcoholism has been thought to be the result of poor moral fiber or lack of willpower. Alcohol is a simple, two-carbon molecule, and neither physicians nor scientists could understand why it has such an insidious and devastating effect on the body and personality. Only recently has research begun to reveal alcoholism in its true light: a deficiency disease, often genetic in ...

متن کامل

A new specialized cell-matrix interaction in actively resorbing osteoclasts.

We have identified a novel cell-matrix interaction in activated osteoclasts. Resorbing osteoclasts maintain a barrier adjacent to the bone surface that prevents the leakage of secreted protons and proteases from the resorption area. Using a series of fluorescent dyes of known molecular mass and different surface charge we established that negatively charged molecules with M(r )up to 10,000 rapi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Bone Research

سال: 2013

ISSN: 2095-4700,2095-6231

DOI: 10.4248/br201301003